GENERAL CATALOGUE
FTO-IN-14
HY-172399 · 50 mg
MedChemExpress · Cat: HY-172399
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Manufacturer product page
medchemexpress.com/fto-in-14.htmlCatalog No: HY-172399
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
FTO-IN-14 Compound F97 is the inhibitor for the RNA demethylase Fat mass and obesity-associated protein FTO with IC50 of 0.45 ?M. FTO-IN-14 regulates the protein expression of ASB2, RARA and MYC. FTO-IN-14 exhibits antiproliferative activity in AML cancer cells IC50 for MOLM13, NB4, HEL, OCI-AML3, MV4-11 and MONOMAC6 is 0.7-5.5 ?M , induces apoptosis in NB4 cell. FTO-IN-14 exhibits antitumor activity in mouse NB4 xenograft models.
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