GENERAL CATALOGUE
FXR agonist 12
HY-164799 · 50 mg
MedChemExpress · Cat: HY-164799
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medchemexpress.com/fxr-agonist-12.html
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Catalog No: HY-164799
CAS No: 1831862-88-4
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
FXR agonist 12 Compound C7 is the orally active agonist for FXR. FXR agonist 12 down-regulates bile acid synthesis-related genes, and up-regulates bile acid transport-related genes in HepG2 cells. FXR agonist 12 improves ANIT-induced cholestasis, ameliorates the liver damage and fibrosis in mouse NASH models.
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