GENERAL CATALOGUE
FXR antagonist 1
HY-151481 · 5 mg
MedChemExpress · Cat: HY-151481
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Manufacturer product page
medchemexpress.com/fxr-antagonist-1.htmlCatalog No: HY-151481
CAS No: 2295804-68-9
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
FXR antagonist 1 compound F6 is an orally active and selective intestinal FXR antagonist IC50=2.1 ?M . FXR antagonist 1 selectively inhibits intestinal FXR signalling through antagonism of intestinal FXR and feedback activation of hepatic FXR to improve hepatic steatosis, inflammation and fibrosis in NASH nonalcoholic steatohepatitis models. FXR antagonist 1 can be used in NASH studies.
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