G6PD Mouse Monoclonal Antibody

Description

EnkiLife offers the G6PD Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rabbit species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: G6PD1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.