GENERAL CATALOGUE
G907
HY-125176 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-125176
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medchemexpress.com/g907.htmlCatalog No: HY-125176
CAS No: 2244035-16-1
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
G907 is a selective antagonist of ATP-binding cassette ABC transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket.
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