GADD45A (6C3) Mouse Monoclonal Antibody

Description

EnkiLife offers the GADD45A (6C3) Mouse Monoclonal Antibody. This antibody reacts with Transfected species and is suitable for WB application. Alternative Names of Immunogen: DDIT1; GADD45. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Research Area: Epigenetics and Nuclear Signaling