GENERAL CATALOGUE
Gal-ARV-771
HY-158331 · 50 mg
MedChemExpress · Cat: HY-158331
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medchemexpress.com/gal-arv-771.html
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Catalog No: HY-158331
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Gal-ARV-771, PROTAC prodrug, is a gal modified ARV-771 HY-100972 . Gal-ARV-771 can be activated in SA-?-Gal-expressed cancer senescent cells to release ARV-771. Gal-ARV-771 induces selective degradation of BRD4 protein by the ubiquitin-proteasome pathway in senescent cells. Gal-ARV-771 promotes apoptosis of senescent cancer cells.
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