GENERAL CATALOGUE
Galeterone
HY-70006 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-70006
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/TOK-001.htmlCatalog No: HY-70006
CAS No: 851983-85-2
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Galeterone TOK-001 is a potent, orally active molecular glue degrader, which degrades androgen receptor AR and its splice variants AR-Vs and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. Galeterone also functions as a CYP17 inhibitor IC50 = 47 nM . Galeterone induces cell apoptosis. Galeterone inhibits tumor growth in human prostate cancer xenograft mouse models. Galeterone can be used for castration resistant prostate cancer CRPC and pancreatic ductal adenocarcinoma PDAC research 1 2 .