Gamma-Mangostin (Standard)

Description

Gamma-Mangostin Standard is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A 5-HT2A receptor antagonist and potent epoxidase 2 COX-2 inhibitor, as well as a transthyroxin protein TTR profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine T4 -binding sites and stabilized the TTR tetramer. Gamma-Mangostin inhibits 3H spiperone binding to cultured rat aortic myocytes IC50=3.5 nM and reduces The perfusion pressure response of rat coronary artery to 5-HT2A IC50=0.32 ?M . Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes.