GENERAL CATALOGUE
Ganoderic acid D
HY-N1511 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N1511
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Catalog No: HY-N1511
CAS No: 108340-60-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D CypD by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
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