GENERAL CATALOGUE
Garcinone C
HY-N6954 · 5 mg
MedChemExpress · Cat: HY-N6954
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Catalog No: HY-N6954
CAS No: 76996-27-5
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma NPC cell lines CNE1, CNE2, HK1 and HONE1 in a time? and dose?dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active.
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