GENERAL CATALOGUE
GBR-401
HY-P991542 · 1 mg
MedChemExpress · Cat: HY-P991542
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medchemexpress.com/gbr-401.html
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Catalog No: HY-P991542
CAS No: 1931954-95-8
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for Fc?RIIIa. GBR-401 exerts a potent in vitro and in vivo cytotoxic activity against various B-cell malignancies. GBR-401 induces cell death by antibody dependent cellular cytotoxicity ADCC and direct killing effect. GBR-401 demonstrates potent activity of depleting malignant B cells and prolongs mice survival in multiple xenograft severe combined immunodeficiency SCID mice models.
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