GENERAL CATALOGUE
GDC-0623
HY-15610 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15610
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Catalog No: HY-15610
CAS No: 1168091-68-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GDC-0623 RG 7421 is a potent, ATP-uncompetitive inhibitor of MEK1 Ki=0.13 nM, +ATP , and displays 6-fold weaker potency against HCT116 KRAS G13D , EC50=42 nM versus A375 BRAFV600E, EC50=7 nM .
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