GENERAL CATALOGUE
GDC-3280
HY-160851 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-160851
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medchemexpress.com/ak3287.htmlCatalog No: HY-160851
CAS No: 1590403-33-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GDC-3280 AK3287; AKEX0011 is an orally active compound based on Pirfenidone HY-B0673 s phenyl pyridone scaffold. GDC-3280 alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 MAPK pathway and regulating macrophage polarization. GDC-3280 exhibits anti-inflammatory and anti-fibrotic effects.