GENERAL CATALOGUE
Gefitinib
HY-50895 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-50895
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Catalog No: HY-50895
CAS No: 184475-35-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Gefitinib ZD1839 is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth IC50 of 54 nM and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .
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