GENERAL CATALOGUE
Gefitinib hydrochloride
HY-50895A · 10 mM * 1 mL in Water
MedChemExpress · Cat: HY-50895A
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medchemexpress.com/Gefitinib-hydrochloride.htmlCatalog No: HY-50895A
CAS No: 184475-55-6
Category: JAK STAT Signaling
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress
Description
Gefitinib hydrochloride ZD1839 hydrochloride is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth IC50 of 54 nM and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity.
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