GHSR-1a agonist-1

Description

GHSR-1a agonist-1 Compound 4b is an orally active agonist of the human growth hormone secretagogue receptor 1a GHSR-1a , with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children.