GENERAL CATALOGUE
GK444
HY-155328 · 50 mg
MedChemExpress · Cat: HY-155328
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medchemexpress.com/gk444.htmlCatalog No: HY-155328
CAS No: 3032392-39-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
GK444 Compound 15a is a HDAC1/2 inhibitor IC50: 100 and 92 nM for HDAC1/2 respectively . GK444 inhibits Caco-2 cells with IC50 of 4.1 ?M. GK444 also reduces TGF-?1 induced COL1A1 mRNA levels in primary normal human lung fibroblasts. GK444 inhibits Bleomycin HY-108345 -induced lung fibrosis in mice.
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