GENERAL CATALOGUE
GK563
HY-138990 · 50 mg
MedChemExpress · Cat: HY-138990
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medchemexpress.com/gk563.html
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Catalog No: HY-138990
CAS No: 2351820-19-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
GK563 is a selective Ca2+-independent phospholipase A2 GVIA iPLA2 inhibitor with an IC50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA2 than GIVA cPLA2. GK563 reduces ?-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.
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