GENERAL CATALOGUE
GKA50
HY-15671 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15671
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Catalog No: HY-15671
CAS No: 851884-87-2
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GKA50 is a potent glucokinase activator EC50=33 nM at 5 mM glucose . GKA50 stimulates insulin release from mouse islets of Langerhans. GKA50 is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca2+-dependent modulator of insulin secretion. GKA50 shows significant glucose lowering in high fat fed female rats.
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