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GKA50 quarterhydrate
GENERAL CATALOGUE

GKA50 quarterhydrate

HY-15671A · 1 mg

MedChemExpress · Cat: HY-15671A

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Catalog No: HY-15671A
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

GKA50 quarterhydrate is a potent glucokinase activator EC50=33 nM at 5 mM glucose and stimulates insulin release from mouse islets of Langerhans. GKA50 quarterhydrate is a glucose-like activator of beta-cell metabolism in rodent and human islets and a Ca2+-dependent modulator of insulin secretion. GKA50 quarterhydrate shows significant glucose lowering in high fat fed female rats.

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