GENERAL CATALOGUE
GL-V9
HY-126876 · 50 mg
MedChemExpress · Cat: HY-126876
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medchemexpress.com/gl-v9.html
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Catalog No: HY-126876
CAS No: 1178583-19-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
GL-V9 inhibits proliferation of HepG2 cell IC50 is 35.2 ?M through induction of apoptosis and cell cycle arrest at G2/M phase. GL-V9 regulates mitochondrial membrane potential and increases the production of intracellular reactive oxygen species. GL-V9 inhibits the pentose phosphate pathway PPP , enhances fatty acid oxidation FAO through activation of AMPK, and thus inhibits the metastasis of cancer cells. GL-V9 exhibits antitumor efficacy in mouse model.
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