GENERAL CATALOGUE
GlcNAc-MurNAc
HY-175222 · 1 mg
MedChemExpress · Cat: HY-175222
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Catalog No: HY-175222
CAS No: 41137-10-4
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
GlcNAc-MurNAc, a disaccharide, is a TLR4 agonist with a Kd of 383 ?M for murine TLR4. GlcNAc-MurNAc directly binds to TLR4 and activates its downstream NF-?B and IRF pathways. GlcNAc-MurNAc improves Dextran sulfate sodium salt DSS HY-116282C -induced colitis in mice through a TLR4-dependent mechanism. GlcNAc-MurNAc can be used for the study of inflammatory bowel disease.
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