GENERAL CATALOGUE
Glibenclamide
HY-15206 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15206
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Catalog No: HY-15206
CAS No: 10238-21-8
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Glibenclamide Glyburide is an orally active ATP-sensitive K+ channel KATP inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein CFTR . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.
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