[Glp5,(Me)Phe8,Sar9] Substance P (5-11)

Description

Glp5, Me Phe8,Sar9 Substance P 5-11 DiMe-C7 is a Substance P HY-P0201 analogue that has approximately the same effects as Substance P HY-P0201 on neurokinin 1 receptor NK1R in rat brain, but with a much longer duration of action. Glp5, Me Phe8,Sar9 Substance P 5-11 selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. Glp5, Me Phe8,Sar9 Substance P 5-11 also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.