GENERAL CATALOGUE
Glucocerebrosidase-IN-2
HY-156020 · 1 mg
MedChemExpress · Cat: HY-156020
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medchemexpress.com/glucocerebrosidase-in-2.htmlCatalog No: HY-156020
CAS No: 851185-20-1
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress
Description
Glucocerebrosidase-IN-2 compound 12 is a quinazoline analogue and an inhibitor of glucocerebrosidase GC . Glucocerebrosidase-IN-2 has the potential to improve GC translocation to lysosomes in Gaucher disease patient-derived cells mostly carrying the N370S mutation . Glucocerebrosidase-IN-2 inhibits the hydrolysis of 4-methylumbelliferone ?-D-glucopyranoside 4MU and fluorescent glycosylceramide FlourGC in N370S mutant tissues with an AC50 of 25.29 ?M.
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