
![?-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE](https://file.medchemexpress.com/product_pic/hy-155313.gif)
HY-155313 · 50 mg
MedChemExpress · Cat: HY-155313
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medchemexpress.com/%CE%B2-glucuronide-nb-bis-n-me-methyl-est...Description
?-Glucuronide-NB-bis N Me -methyl ester -MMAE compound 20 is auristatins-glucuronide conjugate. Antitumor agent-122 shows in vitro antiproliferative activities against ?-glucuronidase pretreated and untreated cancer cells with an IC50 value of 5.7 nM - 9.7 nM. Antitumor agent-122 shows potent antitumor efficacy in HCT-116 xenograft mouse model without inducing side effects.







