GENERAL CATALOGUE
Glyburide-d3
HY-15206S1 · 1 mg
MedChemExpress · Cat: HY-15206S1
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medchemexpress.com/glyburide-d3.htmlCatalog No: HY-15206S1
CAS No: 1219803-02-7
Category: Autophagy
Pack Size: 1 mg
Brand: MedChemExpress
Description
Glyburide-d3 is the deuterium labeled Glibenclamide. Glibenclamide Glyburide is an orally active ATP-sensitive K+ channel KATP inhibitor and can be used for the research of diabetes and obesity 1 . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein CFTR 3 . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability 4 . Glibenclamide can induce autophagy 5 .
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