GENERAL CATALOGUE
GN44028
HY-110266 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-110266
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Catalog No: HY-110266
CAS No: 1421448-26-1
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GN44028 is a potent and orally active hypoxia inducible factor HIF -1? inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1? transcriptional activity without suppressing HIF-1? mRNA expression, HIF-1? protein accumulation, or HIF-1?/HIF-1? heterodimerization. GN44028 can be used in the research of cancers.
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