GENERAL CATALOGUE
GNE-783
HY-15882 · 50 mg
MedChemExpress · Cat: HY-15882
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medchemexpress.com/gne-783.html
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Catalog No: HY-15882
CAS No: 1200127-66-7
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
GNE-783 is a selective CHK1 inhibitor that enhances the activity of gemcitabine. GNE-783 improves the efficacy of anti-metabolite DNA damage drugs by inactivating S-phase and G2-phase cell cycle checkpoints following DNA damage. GNE-783 selectively enhances the chemical synergy of certain drugs in different tumor types, for example, enhancing the activity of temozolomide only in melanoma cell lines.
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