GENERAL CATALOGUE
GNF-2-deg
HY-161804 · 50 mg
MedChemExpress · Cat: HY-161804
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/gnf-2-deg.html
Sponsored
Catalog No: HY-161804
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
GNF-2-deg is a PROTAC degrader for dengue virus envelope protein DENV E protein with DC50 of 0.83 ?M. GNF-2-deg prevents viral entry by inhibiting E-mediated membrane fusion, prevents virion production by protein degradation, and thereby exhibits antiviral activity against DENV 2 with EC90 of 3.5 ?M. GNF-2-deg exhibits antiviral activity against ZIKV, JEV, WNV and YFV with EC90 of 1.96-7.79 ?M. Pink: ligand for target protein HY-161805 ; Black: linker HY-42149 ; Blue: ligand for E3 ligase HY-23095
More from MedChemExpress
Amodiaquine-d10 hydrochloride
HY-B1322AS1
Anti-infection
Influenza A virus-IN-16
HY-172913
Anti-infection
Cytochalasin D
HY-N6682
Anti-infection
Entecavir
HY-13623
Anti-infection
Chlorobutanol hemihydrate
HY-W089856
Anti-infection
GNF-2
HY-11007
Anti-infection
Eupatarone
HY-119901
Anti-infection
Niranthin (Standard)
HY-N6054R
Anti-infection