gp130/CD130/IL-6 R beta, His, Human

Description

gp130 is a common signal transducing component of the functional receptor complexes for the interleukin IL -6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor LIF , oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.