GENERAL CATALOGUE
GPI-1046
HY-124619 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124619
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medchemexpress.com/gpi-1046.htmlCatalog No: HY-124619
CAS No: 186452-09-5
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 GLT1 in the prefrontal cortex PFC and nucleus accumbens core NAc-core . GPI-1046 improves human immunodeficiency virus HIV -associated sensory neuropathy HIV-SN by attenuating store-operated calcium SOC entry. GPI-1046 has neuroprotective activity.
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