GENERAL CATALOGUE
GPP78
HY-14374 · 5 mg (11.38 mM * 1 mL in Methanol)
MedChemExpress · Cat: HY-14374
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Catalog No: HY-14374
CAS No: 1202580-59-3
Category: Autophagy
Pack Size: 5 mg (11.38 mM * 1 mL in Methanol)
Brand: MedChemExpress
Description
GPP78 CAY10618 is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide NAD depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects.
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