GENERAL CATALOGUE
GPR183 antagonist-2
HY-162011 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-162011
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Catalog No: HY-162011
CAS No: 2924063-98-7
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GPR183 antagonist-2 compound 32 is a selective GPR183 antagonist with good water solubility and excellent pharmacokinetic properties. GPR183 antagonist-2 significantly reduces paw and joint swelling and gene expression of pro-inflammatory cytokines MCP-1, MMPs, and VEGF in a collagen-induced arthritis CIA mouse model in a dose-dependent manner. GPR183 antagonist-2 can be used in the study of autoimmune diseases.
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