GPR27 Rabbit Polyclonal Antibody

Description

EnkiLife offers the GPR27 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,ICC/IF,ELISA application. Alternative Names of Immunogen: GPR27; SREB1; Probable G-protein coupled receptor 27; Super conserved receptor expressed in brain 1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000 Background: GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010],function:Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum.,