GPR43 Rabbit Polyclonal Antibody

Description

EnkiLife offers the GPR43 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for ICC/IF,ELISA application. Alternative Names of Immunogen: FFAR2; GPR43; Free fatty acid receptor 2; G-protein coupled receptor 43. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000 Background: This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009],function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.,