

HY-173556 · 5 mg
MedChemExpress · Cat: HY-173556
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medchemexpress.com/gpr84-agonist-2.html
Description
GPR84 agonist-2 Compound 8e is a highly selective GPR84 agonist with an EC50 value of 7.24 nM. GPR84 agonist-2 activates the G?q signaling pathway, promoting inositol trisphosphate IP3 production and calcium release and enhancing neutrophil chemotaxis and pro-inflammatory cytokine release. GPR84 agonist-2 is promising for research of inflammatory diseases, such as ulcerative colitis and acute lung injury.







