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GPR84 antagonist 2
GENERAL CATALOGUE

GPR84 antagonist 2

HY-145697 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-145697

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Catalog No: HY-145697
CAS No: 2244269-74-5
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

GPR84 antagonist 2 compound 33 is a potent, selective, and orally active GPR84 antagonist IC50=8.95 nM . GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis.

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