GENERAL CATALOGUE
GPX4-IN-17
HY-176758 · 1 mg
MedChemExpress · Cat: HY-176758
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medchemexpress.com/gpx4-in-17.htmlCatalog No: HY-176758
CAS No: 3035800-33-7
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
GPX4-IN-17 Compound 9i is an inhibitor of GPX4 with potent cytotoxicity IC50 = 0.3 nM . GPX4-IN-17 shows strong binding affinity against GPX4 KD = 20.4 nM . GPX4-IN-17 inhibits tumor growth in the xenograft tumor mouse model without detectable cytotoxicity. GPX4-IN-17 can enhance cancer chemotherapy and overcome tumor resistance. GPX4-IN-17 can be studied in antitumor reseach.
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