GENERAL CATALOGUE
GR 159897
HY-107691 · 5 mg
MedChemExpress · Cat: HY-107691
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medchemexpress.com/gr-159897.htmlCatalog No: HY-107691
CAS No: 158848-32-9
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide neurokinin 2 NK2 receptor antagonist. GR 159897 has little or no affinity for NK1 and NK3 receptors. GR 159897 inhibits binding of 3H GR100679 to human NK2 hNK2 -CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction. Anxiolytic-like and anti-tumor effects.
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