GENERAL CATALOGUE
Grapiprant
HY-16781 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-16781
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medchemexpress.com/Grapiprant.html
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Catalog No: HY-16781
CAS No: 415903-37-6
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Grapiprant CJ-023423 is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 PGE2 . Grapiprant displaces 3H -PGE2 1 nM binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment 3 .
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