GRK2 Mouse Monoclonal Antibody

Description

EnkiLife offers the GRK2 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Monkey species and is suitable for WB,IHC,ICC,ELISA application. Alternative Names of Immunogen: GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes