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GRL-07524
GENERAL CATALOGUE

GRL-07524

HY-175031 · 50 mg

MedChemExpress · Cat: HY-175031

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medchemexpress.com/grl-07524.html
Catalog No: HY-175031
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

GRL-07524 Compound 4e is a potent inhibitor of HIV-1 protease Ki = 0.22 nM . GRL-07524 contains oxaspirocyclic carbamates as the P2 ligands. GRL-07524 exhibits good antiviral activity with an EC50 = 210 nM. GRL-07524 binds to the HIV-1 PR active site in one of the four symmetry independent molecules along with key catalytic residues.

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