GENERAL CATALOGUE
GS-9667
HY-19842 · 5 mg
MedChemExpress · Cat: HY-19842
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medchemexpress.com/gs-9667.htmlCatalog No: HY-19842
CAS No: 618380-90-8
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
GS-9667 CVT 3619 , a novel N6-5-substituted adenosine analog, is a selective, partial agonist of the A1 adenosine receptor A1AdoR . GS-9667 binds to adipocyte membranes with high KH=14 nM and low KL=5.4 ?M affinities. GS-9667 reduces cyclic AMP content and release of nonesterified fatty acids from epididymal adipocytes with IC50 values of 6 nM and 44 nM, respectively. GS-9667 inhibits lipolysis and has the potential for Type 2 diabetes T2DM and dyslipidemia via lowering of free fatty acids FFA .
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