GENERAL CATALOGUE
GS143
HY-110261 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-110261
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Catalog No: HY-110261
CAS No: 916232-21-8
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GS143 is a selecAAasAasAAtive I?B? ubiquitination inhibitor with an IC50 of 5.2 ?M for SCF?TrCP1-mediated I?B? ubiquitylation. GS143 supAAasAasAApresses NF-?B actiAAasAasAAvaAAasAasAAtion and tranAAasAasAAscripAAasAasAAtion of tarAAasAasAAget genes and does not inhibit proteasome activity. GS143 has anti-asthma effect.
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