GENERAL CATALOGUE
GSK-3?/HDAC-IN-2
HY-174398 · 50 mg
MedChemExpress · Cat: HY-174398
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medchemexpress.com/gsk-3%CE%B2-hdac-in-2.htmlCatalog No: HY-174398
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
GSK-3?/HDAC-IN-2 is a potent inhibitor of GSK-3? IC50 = 0.04 ?M , HDAC2 IC50 = 1.05 ?M, Ki = 0.070 ?M and HDAC6 IC50 = 1.52 ?M, Ki = 0.017 ?M . GSK-3?/HDAC-IN-2 inhibits HDAC2 and HDAC6 activities and blocks tau hyperphosphorylation. GSK-3?/HDAC-IN-2 exerts neuroprotective effects and shows no significant toxicity. GSK-3?/HDAC-IN-2 can be used in the research of Alzheimers disease.
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