GENERAL CATALOGUE
GSK-3 inhibitor 3
HY-154851 · 5 mg
MedChemExpress · Cat: HY-154851
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Catalog No: HY-154851
CAS No: 2227279-84-5
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3? and GSK-3?, respectively. GSK-3 inhibitor 3 lowers levels of tau protein phosphorylation at S396 in a triple-transgenic mouse AlzheimerAAasAasAas disease model, with IC50 of 10 nM. GSK-3 inhibitor 3 can be used for neurological disease research.
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