GENERAL CATALOGUE
GSK-J4 hydrochloride (Standard)
HY-15648FR · 5 mg
MedChemExpress · Cat: HY-15648FR
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medchemexpress.com/gsk-j4-hydrochloride-standard.html
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Catalog No: HY-15648FR
CAS No: 1797983-09-5
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress
Description
GSK-J4 hydrochloride Standard is the analytical standard of GSK-J4 hydrochloride . This product is intended for research and analytical applications. GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 ?M, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-? production in human primary macrophages with an IC50 of 9 ?M. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1.
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