GENERAL CATALOGUE
GSK046
HY-136571 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136571
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medchemexpress.com/gsk046.htmlCatalog No: HY-136571
CAS No: 2474876-09-8
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GSK046 iBET-BD2 , a chemical probe, is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM BRD2 BD2 , 98 nM BRD3 BD2 , 49 nM BRD4 BD2 and 214 nM BRDT BD2 , respectively. GSK046 has immunomodulatory activity.